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This derivative is usually acetylated, hydroxylated and glucuronidated. Cytochrome P-450 together with CYP3A, may possibly Participate in a significant purpose in clonazepam reduction and oxidation. The elimination 50 %-life of clonazepam is often 30 to 40 hrs. Clonazepam pharmacokinetics are dose-unbiased all through the dosing array. There is not